Opinion of the Scientific Panel on Dietetic Products, Nutrition and Allergies on a request from the Commission related to the Tolerable Upper Intake Level of Nickel
ثبت نشده
چکیده
Nickel has not been shown to be essential for humans. Orally ingested nickel salts can cause adverse effects on kidneys, spleen, lungs and the myeloid system in experimental animals. Furthermore, perinatal mortality was reported to be increased in the offspring of female rats ingesting nickel salts, even at the lowest administered dose (1.3 mg nickel/kg body weight/day). While there is evidence that inhaled nickel salts are carcinogenic in rodents and humans, orally ingested nickel salts have not been shown to be carcinogenic; however the data presently available are very limited.
منابع مشابه
Opinion of the Scientific Panel on Dietetic Products, Nutrition and Allergies on a request from the Commission related to the Tolerable Upper Intake Level of Potassium (Request N° EFSA-Q-2003-018)
Gastrointestinal symptoms (discomfort, mucosal lesions and sometimes ulceration) have been seen in healthy subjects taking some forms of potassium supplements (e.g. slow-release, wax matrix formulations) with doses ranging from about 1 to 5 g potassium per day, or more, but incidence and severity seem to be more dependent on the formulation than on dose. In healthy adults administration of sing...
متن کاملOpinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and materials in Contact with Food on a request from the Commission related to Ferrous bisglycinate as a source of iron for use in the manufacturing of foods
In 2004, The Scientific Panel on Dietetic Products, Nutrition and Allergies (NDA Panel) evaluated the safety of iron in general, when present in fortified foods and food supplements, but considered that the available data were insufficient to establish a tolerable upper intake level for iron. The NDA Panel also indicated there are certain subgroups of the population (men and postmenopausal wome...
متن کاملScientific Committee on Food Scientific Panel on Dietetic Products, Nutrition and Allergies TOLERABLE UPPER INTAKE LEVELS FOR VITAMINS AND MINERALS
متن کامل
Opinion of the safety of ‘synthetic Zeaxanthin as an ingredient in food supplements’ Scientific Opinion of the Panel on Dietetic Products, Nutrition and Allergies
Following a request from European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver a scientific opinion on the safety of ‘Zeaxanthin as an ingredient in food supplements’ (max 20 mg per day) in the context of Regulation (EC) N° 258/97. In particular, EFSA is asked to consider the elements of a scientific nature in the comments/objections raised by Member ...
متن کاملSafety of ‘fungal oil from Mortierella alpina’ Scientific Opinion of the Panel on Dietetic Products, Nutrition and Allergies
Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies of the European Food Safety Authority (EFSA) was asked to deliver a scientific opinion on the safety of ‘fungal oil from Mortierella alpina’. The product, referred to as Fungal Oil SUN-TGA40S, is an arachidonic acid-rich oil obtained by fermentation from the fungus Mortierella alpina and is...
متن کامل